Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes

Authors: Krishna Deo Sharma, Karrer M Alghazali, Rabab N Hamzah, Sahitya Chetan Pandanaboina, Zeid A Nima Alsudani, Malek Muhi, Fumiya Watanabe, Guo-Lei Zhou, Alexandru S Biris, Jennifer Yanhua Xie. Publication: Nanomaterials. 2022 Mar 11;12(6):929. Publication Date: March 11, 2022. DOI: 10.3390/nano12060929 Abstract: Gold nanorods (AuNRs) have been proposed to promote stem cell differentiation in vitro Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes

Tracking gold nanorods’ interaction with large 3D pancreatic-stromal tumor spheroids by multimodal imaging: Fluorescence, photoacoustic, and photothermal microscopies

Authors: Emilie Darrigues, Zeid A. Nima, Dmitry A. Nedosekin, Fumiya Watanabe, Karrer M. Alghazali, Vladimir P. Zharov, Alexandru S. Biris Publication: Scientific Reports, Volume 10, Issue 1, 2020 Abstract: Pancreatic cancer is one of the most complex types of cancers to detect, diagnose, and treat. However, the field of nanomedicine has strong potential to address Tracking gold nanorods’ interaction with large 3D pancreatic-stromal tumor spheroids by multimodal imaging: Fluorescence, photoacoustic, and photothermal microscopies

3D cultures for modeling nanomaterial-based photothermal therapy

Authors: Emilie Darrigues,  Zeid A. Nima, Robert J. Griffin, James M. Anderson, Alexandru S. Biris, and Analiz Rodriguez   Publication: Nanoscale Horiz., 2019, Advance Article, DOI: 10.1039/c9nh00628a Abstract: Photothermal therapy (PTT) is one of the most promising techniques for cancer tumor ablation. Nanoparticles are increasingly being investigated for use with PTT and can serve as theranostic agents. Based 3D cultures for modeling nanomaterial-based photothermal therapy

Plasmonic Nanofactors as Switchable Devices to Promote or Inhibit Neuronal Activity and Function

Authors: Alghazali KM, Hamzah RN, Nima ZA, Steiner R, Dhar M, Anderson DE, Hayar A, Griffin RJ, Biris AS. Publication: Nanomaterials (Basel). 2019 Jul 18;9(7). pii: E1029. doi: 10.3390/nano9071029. Abstract: Gold nanosystems have been investigated extensively for a variety of applications, from specific cancer cell targeting to tissue regeneration. Specifically, a recent and exciting focus Plasmonic Nanofactors as Switchable Devices to Promote or Inhibit Neuronal Activity and Function

Plasmonic Nano Surface for Neuronal Differentiation and Manipulation

Authors: Sahitya Chetan Pandanaboina, Karrer M. Alghazali, Zeid A. Nima, Raad A. Alawajji, Krishna Deo Sharma, Fumiya Watanabe, Viney Saini, Alexandru S. Biris, Malathi Srivatsan Publication: Nanomedicine: Nanotechnology, Biology and Medicine, Volume 21, October 2019, 102048 Abstract: Neurodegenerative diseases and traumatic brain injuries can destroy neurons, resulting in sensory and motor function loss. Transplantation of differentiated Plasmonic Nano Surface for Neuronal Differentiation and Manipulation

Using Nano- and Micro-Titanium Dioxide (TiO2) in Concrete to Reduce Air Pollution

Authors: Hala N. Elia, Anindya Ghosh, Amin k. Akhnoukh, and Zeid A. Nima Publication: J Nanomed Nanotechnol, Volume 9 • Issue 3 • 1000505 Abstract: A crucial element in construction, tunnels, roads, and more, concrete has become one of the most important materials in the world. At the same time, air pollution, particularly in crowded Using Nano- and Micro-Titanium Dioxide (TiO2) in Concrete to Reduce Air Pollution

X-ray Photoelectron Spectroscopy and Transmission Electron Microscopy analysis of silver-coated gold nanorods designed for bionanotechnology applications

Authors: Fumiya Watanabe, Zeid A. Nima, Takumi Honda, Masatoshi Mitsuhara, Minoru Nishida, and Alexandru S. Biris Publication: Nanotechnology, Volume 28, Number 2, doi:10.1088/1361-6528/28/2/025704 Abstract: Multicomponent nano-agents were designed and built via a core–shell approach to enhance their surface enhanced Raman scattering (SERS) signals. These nano-agents had 36 nm × 12 nm gold nanorod cores coated by 4 nm thick silver shell films and a subsequent thin bifunctional thiolated X-ray Photoelectron Spectroscopy and Transmission Electron Microscopy analysis of silver-coated gold nanorods designed for bionanotechnology applications

Carbon nanotubes as carriers of Panax ginseng metabolites and enhancers of ginsenosides Rb1 and Rg1 anti-cancer activity

Authors: Lahiani MH, Eassa S, Parnell C, Nima Z, Ghosh A, Biris AS, Khodakovskaya MV Publication: Nanotechnology. 2017 Jan 6;28(1):015101. Epub 2016 Nov 28. Abstract: A major benefit to nanomaterial based-medicine is the ability to provide nanosized vehicles for sporadic metabolites. Here, we describe how the conjugation of valuable ginseng secondary metabolites (ginsenoside Rb1 or Rg1) with carbon nanotubes (CNT) can enhance their anti-proliferative Carbon nanotubes as carriers of Panax ginseng metabolites and enhancers of ginsenosides Rb1 and Rg1 anti-cancer activity

Bone-tissue Engineering: Complex Tunable Structural and Biological Responses to Injury, Drug Delivery, and Cell-based Therapies

Authors: Karrer M. Alghazali, Zeid A. Nima, Rabab N. Hamzah, Madhu S. Dhar, David E. Anderson, and Alexandru S. Biris Publication: Drug Metabolism Reviews, Volume 47, Issue 4 Abstract: Bone loss and failure of proper bone healing continues to be a significant medical condition in need of solutions that can be implemented successfully both in human and Bone-tissue Engineering: Complex Tunable Structural and Biological Responses to Injury, Drug Delivery, and Cell-based Therapies

Photothermal Confocal Multicolor Microscopy of Nanoparticles and Nanodrugs in Live Cells

Authors: Dmitry A. Nedosekin, Stephen Foster, Zeid A. Nima, Alexandru S. Biris, Ekaterina I. Galanzha, and Vladimir P. Zharov Publication: Drug Metabolism Reviews, Volume 47, Issue 3 Abstract: Growing biomedical applications of non-fluorescent nanoparticles (NPs) for molecular imaging, disease diagnosis, drug delivery, and theranostics require new tools for real-time detection of nanomaterials, drug nano-carriers, and NP-drug Photothermal Confocal Multicolor Microscopy of Nanoparticles and Nanodrugs in Live Cells